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產(chǎn)品規(guī)格
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BN41257R-100ul
100ul
￥2360.00
交叉反應：Human,Mouse(predicted:Rat) 推薦應用：WB,IHC-P,IHC-F,IF,ELISA
BN41257R-200ul
200ul
￥3490.00
交叉反應：Human,Mouse(predicted:Rat) 推薦應用：WB,IHC-P,IHC-F,IF,ELISA
產(chǎn)品描述
| 英文名稱 | RHBDD3 |
| 中文名稱 | 垂體瘤細胞凋亡抗體 |
| 別 名 | C22orf3; HS984G1A; Pituitary tumor apoptosis; PTAG; RHBD3_HUMAN; RHBDD3; Rhomboid domain containing 3; Rhomboid domain-containing protein 3. |
| 研究領域 | 細胞生物 神經(jīng)生物學 細胞凋亡 轉(zhuǎn)錄調(diào)節(jié)因子 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應 | Human, Mouse, (predicted: Rat, ) |
| 產(chǎn)品應用 | WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 40kDa |
| 細胞定位 | 細胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human RHBDD3:151-250/386 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| PubMed | PubMed |
| 產(chǎn)品介紹 | PTAG is a novel 386 amino acid multi-pass membrane protein that contains one UBA domain and augments drug-induced apoptosis. Cells lacking PTAG have a reduced apoptotic response, thereby causing a predisposition to cell malignancy and resistance to chemotherapeutic interventions, and PTAG plays a role in colorectal tumorigenesis as the majority of primary colorectal tumors lack the PTAG gene. Encoded by a gene located on human chromosome 22, PTAG is often co-expressed with EWS (ewing sarcoma breakpoint region 1), a gene located directly downstream of PTAG. Subcellular Location: Membrane; Multi-pass membrane protein (Potential). Similarity: Contains 1 UBA domain SWISS: Q9Y3P4 Gene ID: 25807 Database links: Entrez Gene: 25807 Human Entrez Gene: 279766 Mouse SwissProt: Q9Y3P4 Human SwissProt: Q8BP97 Mouse Unigene: 106730 Human Unigene: 260866 Mouse Unigene: 9606 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. RHBDD3分子是一個全新的TLR信號途徑的負向調(diào)控蛋白分子,是一個能夠顯著抑制自身免疫性疾病發(fā)生的效應分子,RHBDD3控制機體避免發(fā)生過度的免疫應答、防止自身免疫性疾病的發(fā)生具有重要意義。 |
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