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CD9蛋白抗體

產(chǎn)品貨號：

BN41824R
中文名稱：

CD9蛋白抗體
英文名稱：

Rabbit anti-CD9 Polyclonal antibody
品牌：

Biorigin

貨號

產(chǎn)品規(guī)格

售價

備注
BN41824R-50ul

50ul

￥1486.00

交叉反應(yīng)：Human,Mouse,Rat(predicted:Dog,Pig,Cow,Rabbit,Sheep) 推薦應(yīng)用：WB,IHC-P,IHC-F,IF,Flow-Cyt,ELISA
BN41824R-100ul

100ul

￥2360.00

交叉反應(yīng)：Human,Mouse,Rat(predicted:Dog,Pig,Cow,Rabbit,Sheep) 推薦應(yīng)用：WB,IHC-P,IHC-F,IF,Flow-Cyt,ELISA
BN41824R-200ul

200ul

￥3490.00

交叉反應(yīng)：Human,Mouse,Rat(predicted:Dog,Pig,Cow,Rabbit,Sheep) 推薦應(yīng)用：WB,IHC-P,IHC-F,IF,Flow-Cyt,ELISA

產(chǎn)品描述

英文名稱	CD9
中文名稱	CD9蛋白抗體
別名	Tetraspanin 29; 5H9; 5H9 antigen; Antigen defined by monoclonal; 602 29; Antigen defined by monoclonal; 60229; BA 2; BA2; BTCC 1; BTCC1; CD 9; CD9; CD9 antigen; CD9 antigen p24; CD9 molecule; CD9_HUMAN; Cell growth inhibiting gene 2 protein; Cell growth-inhibiting gene 2 protein; DRAP 27; DRAP27; GIG 2; GIG2; Growth inhibiting gene 2 protein; Leukocyte antigen MIC3; MIC 3; MIC3; Motility related protein; Motility-related protein; MRP 1; MRP-1; MRP1; p24; P24; p24 antigen; Tetraspanin 29; Tetraspanin-29; Tetraspanin29; Tspan 29; Tspan-29; Tspan29.

研究領(lǐng)域	腫瘤細(xì)胞生物免疫學(xué) 發(fā)育生物學(xué) 細(xì)胞表面分子
抗體來源	Rabbit
克隆類型	Polyclonal
交叉反應(yīng)	Human, Mouse, Rat, (predicted: Dog, Pig, Cow, Rabbit, Sheep, )
產(chǎn)品應(yīng)用	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1μg/Test IF=1:100-500 （石蠟切片需做抗原修復(fù)） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分子量	25kDa
細(xì)胞定位	細(xì)胞膜
性狀	Liquid
濃度	1mg/ml
免疫原	KLH conjugated synthetic peptide derived from human CD9:101-200/228 <Extracellular>
亞型	IgG
純化方法	affinity purified by Protein A
儲存液	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMed	PubMed
產(chǎn)品介紹	CD9 antigen is a glycoprotein expressed on the surface of developing B lymphocytes, platelets, monocytes, eosinophils, basophil, stimulated T lymphocytes and by neurons and glial cells in the peripheral nervous system. It belongs to a family of membrane proteins termed tetraspanins which transverse the membrane four times. In pre B cells and platelets, CD9 antigen regulates cell activation and aggregation possibly through an association with the integrin CD41 / CD61 (GPIIb / GPIIIa). It also regulates cell motility in a variety of cell lines, and appears to be an important regulator of Schwann cell behaviour in peripheral nerve. Function: Involved in platelet activation and aggregation. Regulates paranodal junction formation. Involved in cell adhesion, cell motility and tumor metastasis. Required for sperm-egg fusion. Subunit: Forms both disulfide-linked homodimers and higher homooligomers as well as heterooligomers with other members of the tetraspanin family. Associates with CR2/CD21 and with PTGFRN/CD9P1. Interacts directly with IGSF8. Subcellular Location: Membrane; Multi-pass membrane protein. Tissue Specificity: Expressed by a variety of hematopoietic and epithelial cells. Post-translational modifications: Protein exists in three forms with molecular masses between 22 and 27 kDa, and is known to carry covalently linked fatty acids. Similarity: Belongs to the tetraspanin (TM4SF) family. SWISS: P21926 Gene ID: 928 Database links: Entrez Gene: 928 Human Entrez Gene: 12527 Mouse Entrez Gene: 24936 Rat Omim: 143030 Human SwissProt: P21926 Human SwissProt: P40240 Mouse SwissProt: P40241 Rat Unigene: 114286 Human Unigene: 210676 Mouse Unigene: 404614 Mouse Unigene: 2091 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. CD9是一種普遍存在于細(xì)胞膜表面屬于四跨膜超蛋白家族的細(xì)胞表面糖蛋白, 參與質(zhì)膜的融合過程，在細(xì)胞膜生物學(xué)中發(fā)揮重要作用。近年來經(jīng)研究發(fā)現(xiàn)，CD9與多種腫瘤轉(zhuǎn)移有關(guān)，故稱腫瘤轉(zhuǎn)移抑制基因亦稱抗腫瘤轉(zhuǎn)移基因。是一個新的腫瘤轉(zhuǎn)移抑制基因膜運動相關(guān)蛋白-1(CD9/MRP-1)，其分子功能還有待于進(jìn)一步研究。CD9主要在早B細(xì)胞、活化T淋巴細(xì)胞、嗜酸性粒細(xì)胞、嗜堿性粒細(xì)胞和血小板表達(dá)。